Targeting the Enzyme of Cancer

Medical News Today published an article written by Catharine Paddock PhD and fact checked by Carolyn Robertson on targeting the enzyme to halt ovarian cancer. The most common form of ovarian cancer is high-grade serous. The cancer develops resistance to chemotherapy and returns in most people. The new study raises hopes for using a different kind of treatment.

Researchers found in working with cell cultures that an enzyme they call isocitrate dehydrogenase 1 (IDH1) encourages the proliferation of high-grade serous ovarian cancer cells. When the cell was blocked by the enzyme chemically or by silencing its gene, the cancer cells lost …read more