The Health Benefits of TMG: Homocysteine Reduction and More

Trimethylglycine (TMG), also known as betaine or glycine betaine, is a derivative of the amino acid glycine. The compound was originally discovered in sugar beets. It also occurs in such foods as quinoa, wheat bran and spinach. Trimethylglycine is made in the bodies of most organisms from the nutrient choline.

Clinical Significance of Trimethylglycine

Trimethylglycine is a methyl donor, which, by definition, donates methyl groups that consist of 1 carbon and 3 hydrogen atoms in a process known as methylation. Remethylation of homocysteine, a toxic amino acid formed from the essential amino acid methionine, can be accomplished via a pathway that involves …read more