Methylation capacity’s importance in exercise adaptation

In the human body, methylation refers to the donation of a methyl group (an alkyl composed of one carbon bound to three hydrogens) to some substrate, facilitated by methylating enzymes (cofactors for which include folate, vitamin B6, and vitamin B12). An introduction to the entirety of methylation processes in the body is obviously outside of this article’s scope, so let’s limit our focus to the roles of methyl groups in genetic expression, protein function, and free radical quenching. Methyl groups and their donors can be seen simplistically as one of the body’s chief organizers which direct many facets …read more