Noble Nobiletin: Top 5 Health Benefits from this Citrus Flavonoid

Noble Nobiletin: Top 5 Health Benefits from this Citrus Flavonoid

Nobiletin, like tangeretin, is a type of flavonoid known as a polymethoxylated flavone, which is
found in citrus fruit, including its peel. In addition to its antioxidant property, nobiletin has antitumor, anti-inflammatory and other effects.

1) Anti-Inflammatory

Research has determined that nobiletin’s anti-inflammatory effect is similar to that of corticosteroid drugs and that its upregulation of the matrix metalloproteinase inhibitor TIMP-1 is a unique action. (Matrix metalloproteinases are enzymes responsible for the degradation of collagen, one of the main structural components of connective tissue.) In rats with induced rheumatoid arthritis, treatment …read more