Particular Old Protein May Cause Cancer

An intracellular protein previously known to transport molecules to and from various cellular organelles in the normal cells may also cause cancer development by interfering with an important growth-control pathway.

Mutation of RAB35 as a stimulus for cancer

The Institute of Whitehead and Memorial Sloan-Kettering Cancer Center conducted an in-depth research on cell signaling pathway regulators including PI3K/AKT that promotes cell division and inhibits apoptosis. The researchers found maximum activity of these regulators in cancer cells and particularly the role of protein RAB35 in cancer formation. An online journal “Science” published their study findings.

According to Douglas Wheeler, A former science student in …read more